Rice University logo Bioengineering, George R. Brown School of Engineering
 
Top blue bar image Bioengineering
 

Workshop on Precision Genome Editing  

    BAO Genome Editing Event
 

Workshop Organizers:

  • Dr. Gang Bao, Rice University
  • Dr. Jason Heaney, Baylor College of Medicine
  • Dr. Jan Parker-Thornburg, UT MD Anderson Cancer Center
  • Dr. Brian Davis, UT Health Science Center at Houston
  • Dr. David Reiner, Texas A&M Health Science Center

Significant strengths exist in the Houston-Galveston area research community in genome editing, including the Genome Editing Core at Rice University, Mouse Embryonic Stem Cell Core and Cell-Based Assay Screening Service at Baylor College of Medicine, Genetically Engineered Mouse Facility at UT MD Anderson, Center for Stem Cell and Regenerative Medicine at UTHealth, and Targeted Genomics Core at Texas A&M Institute for Genomic Medicine (TIGM). The goals of this workshop are to showcase the genome editing activities in our biomedical research community, help integrate the genome editing capabilities, and develop a consortium in precision genome editing research and education. Register at: https://register.eventarc.com/32050/precision-genome-editing-workshop  

Goals of the workshop

  • Showcase genome editing activities in the Houston-Galveston area research community
  • Help integrate genome editing capabilities in our biomedical research community
  • Develop a consortium in precision genome editing research and education

Event Program 

12:00 - 1:00 pmLunch (optional)
1:00 - 1:10  Opening remarks
1:10 - 1:25Genome editing for treating single-gene disorders
Dr. Gang Bao, Rice University
1:25 - 1:40Sequence-specific correction of mutations in stem cells from patients with inherited lung or blood diseases
Dr. Brian Davis, UT Health Science Center at Houston
1:40 - 1:55CRISPR/Cas9 genome editing in mice: Lessons learned from KOMP2
Dr. Jason Heaney, Baylor College of Medicine
1:55 - 2:10Generating mouse models using CRISPR/Cas9
Dr. Jan Parker-Thornburg, UT MD Anderson Cancer Center
2:10 - 2:25Gene editing in disease animal models and therapy
Dr. Mingyao Liu, Texas A&M Health Science Center
2:25 - 2:40Modeling human disease with precise genome editing
Dr. Rui Chen, Baylor College of Medicine
2:40 - 2:55Should we abandon high throughput siRNA screen for high throughput CRISPR screens?
Dr. Geoffrey Bartholomeusz, UT MD Anderson Cancer Center
2:55 - 3:15Break
3:15 - 3:30Model system knock-ins: fluorescent tags, domain swaps, missense alleles
Dr. David Reiner, Texas A&M Health Science Center
3:30 - 3:45Quantifying on- and off-target cleavage in nuclease-based genome editing
Dr. Ciaran Lee, Rice University
3:45 - 4:00Using CRISPR/Cas9 for targeted gene repair: good versus bad “on”- target genomic changes
Dr. Paul Overbeek, Baylor College of Medicine
4:00 - 4:15Generation and validation of skeletal myogenic reporter hIPS lines using CRISPR/CAS9 system
Dr. Radbod Darabi, UT Health Science Center at Houston
4:15 - 4:30Efficient generation of human iPSC NEUROG2 knockin reporters by the CRISPR system
Dr. Ying Liu, UT Health Science Center at Houston
4:30 - 4:45Post-Gene-Trap Era at TIGM: Genome Editing
Dr. Ben Morpurgo, Texas A&M Institute for Genomic Medicine (TIGM)
4:45 - 5:00Thermo Fisher Genome Engineering – latest products and technologies
Chris Marino, Thermo Fisher Scientific
5:00 - 6:00Happy hour