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Bilal Ghosn

Bilal GhosnLecturer

Postdoctoral Fellow, Bioengineering, University of Washington (2009-2013)
Ph.D., Biomedical Engineering, University of Texas at Austin (2009)
M.S., Biological & Agricultural Engineering, Louisiana State University (2004)
B.S., Biological Engineering, Louisiana State University (2002) 

Bio Sketch

Bilal Ghosn brings valuable basic and translational research experience to his role as lecturer in undergraduate bioengineering education, laboratory techniques and experimentation, as well as capstone engineering design and application. He is also developing a freshman writing course focused on design aspects of universal engineering for patients with disabilities.

Ghosn joined the Rice University Department of Bioengineering in 2013. As a lecturer, he has undertaken active project-based laboratory modules in bioprocessing and tissue culture. He has also developed a new course in molecular techniques specific to bioengineering that emphasizes the physics of biomedical optics and the understanding and development of analytic techniques for optimal diagnostics. He is the recipient of the 2015 Department of Bioengineering Excellence in Teaching Award.

Ghosn’s strong record of published work as a postdoctoral researcher at the University of Washington and as a doctoral graduate student at the University of Texas, Austin focused on advances in tissue engineering and biomaterials, drug delivery, and immunobioengineering techniques. His portfolio includes 12 journal publications, four patent applications and co-authorship on a book chapter in Biomaterials Science: An Introduction to Materials in Medicine, third edition.

Ghosn’s research projects in the laboratories of Professors Patrick S. Stayton and Allan S. Hoffman at the University of Washington involved the development of stimuli-responsive synthetic polymers for the intracellular delivery of a variety of biomacromolecules including siRNA as well as anti-cancer antibodies and enzymes. His work also included the development of targeted carriers incorporating carbohydrates. These delivery vehicles were developed by the revolutionary method of Reversible Addition-Fragmentation chain-Transfer (RAFT) polymerization for the production of highly reproducible and controlled polymers to treat disorders, such as cancer and lung disease. These projects were conducted in collaboration with the University of Washington School of Medicine and the Fred Hutchinson Cancer Research Center.

Ghosn has a doctorate in biomedical engineering from the University of Texas, Austin. His investigations in the laboratories of Professor Krishnendu Roy and Professor Lisa Brannon-Peppas, included the development of a novel amine modified chitosan for enhanced nucleic acid therapy and contrast agent delivery in collaboration with Ambion, Inc. and Rice University’s Department of Bioengineering. These modified natural polymers have been shown to provide effective systemic siRNA-mediated gene silencing as well as tools for providing tissue permeation to provide an opportunity for more accurate cancer diagnosis in biopsy samples. His work also included the development of microparticles for the delivery of DNA vaccines in collaboration with the University of Texas MD Anderson Cancer Center, which demonstrated significantly enhanced immune responses.

Ghosn holds a master’s in biological and agricultural engineering and a bachelor’s in biological engineering from Louisiana State University.